Abstract: In view of the teaching pain points of the course “Fundamentals of Mechanical Design”, the teaching idea of “student-centered, application-oriented, integration of production and education, and continuous innovation” is proposed, and on the basis of the CDIO engineering education model of “modularization of teaching content, project-based teaching process, and practical teaching objectives”, the teaching mode of “5E” + OBE is integrated, and the theoretical knowledge and practical application are organically integrated with specific cases as the starting point, and students are guided to think independently, aiming to cultivate application-oriented scientific and technological talents.