Abstract: With the comprehensive and rapid development of the intelligent manufacturing technology industry, the state has put forward more stringent and urgent requirements for cultivating high-quality innovative and entrepreneurial talents. This paper summarizes the importance of innovation and entrepreneurship education to the cultivation of mechanical professionals, focuses on the shortcomings in the curriculum knowledge system and teachers in the implementation of innovation and entrepreneurship education, and finally discusses the construction of education mode, platform and teaching team, optimizes the training mode of innovation and entrepreneurship education, and provides reference for the cultivation of innovation and entrepreneurship education talents.