Abstract: Corn southern rust pathogens in Xintai City, Shandong Province, were systematically identified and analyzed through various methods, such as morphological observation, pathogenicity measurement, and molecular identification．Results indicated that corn southern rust in this region was mainly caused by Puccinia polysora, spread and development of this pathogen affects corn production significantly．To better understand occurrence of corn southern rust, extensive field surveys were conducted to systematically collect data related to climatic factors, and to analyze correlation between factors and disease incidence．Results showed that spread and propagation of corn southern rust were accelerated with temperature ranging from 19.0～25.8 °C, relative humidity above 70%, and frequent cloudy and rainy weather．Comparative effects of four chemical pesticides on control of southern corn rust showed that 30% azoxystrobin-pentaconazole suspension had the highest preventive effect of 84.32%, followed by 250 g/L propiconazole emulsified oil with the second preventive effect of 80.45%, and difference between two pesticides was significant．The highest corn yield of 9219.6 kg/hm² was achieved after using 30% azoxystrobin-pentaconazole suspension．The second highest corn yield treated 250 g/L propiconazole emulsified oil spraying was 9021.15 kg/hm², and difference between two pesticides was not significant．