Abstract: Aiming at issues in open experiment teaching such as significant differences in students' foundational knowledege, limited effectiveness of traditional teaching models, and singularity of performance assessment methods, with artificial intelligence technology as core support and intelligent teaching platforms as foundation, teaching reform were advanced．A series of measures, such as virtual simulation platform development, pre-class preview resources delivery, hybrid teaching model exploration combining online and offline, and construction of a diversified assessment system, and establishment of online teaching evaluation and feedback mechanisms, have effectively stimulated students' learning enthusiasm and active participation．These efforts have successfully enhanced teaching flexibility and interactivity, improved open experimental teaching quality, and provided valuable experience for continuous improvement of open experimental teaching．