Abstract: Abstract: Centrifugal separator is one kind of filtration equipment that can separate the sediment from high-silt content water based on principles of rotational flow and centrifugal force. In recent years, research on numerical simulation of centrifugal separator is mostly in the fields of petroleum and chemical industry, and focuses on low concentration and mixture multiphase flow model. When using high-silt content water as micro-irrigation water source in water shortage areas, there will be high-silt content water near the centrifugal separator wall and underflow, in such case, low concentration and mixture multiphase flow model is not applicable to the numerical simulation of centrifugal separator that has used for micro-irrigation. Using high-silt content water as micro-irrigation water source, combined with the structure parameters of centrifugal separator, in this article, we established hydromechanics fundamental equation and used finite volume method to discretize and solve it. High concentration turbulence model was selected to analyze the internal flow field characteristics of the centrifugal separator by dividing grids and setting boundary conditions. Numerical simulation results were verified through an experiment, which was carried out in December 2014 at the State Key Laboratory of Water Resources and Hydropower Engineering Science, Wuhan University. XLF200 centrifugal separator was selected with the cylinder diameter of 200 mm, the water outlet diameter of 65 mm, the water inlet diameter of 50 mm, and the bottom outlet diameter of 50 mm. Three different working conditions including the bottom flow diversion ratios of 1.0%, 10.0% and 25.0% were designed. Samples for overflow and bottom flow in 3 different working conditions were taken, and inlet flow, inlet concentration, bottom flow, bottom concentration, and concentration of overflow were measured so as to calculate the separation efficiency. The separation efficiency from the numerical simulation was compared with that obtained from the experiment. The results showed the relative error of the separation efficiency obtained from simulation and experiment was within 10%, indicating that the numerical simulation method was reliable. The separation efficiency was increased gradually with increasing inlet pressure, further verifying the feasibility of numerical simulation. At the inlet pressure was less than 0.3 MPa, the simulated data was consistent with the measured data on the working condition 1 (diversion ratio was 1.0%), but the former was less than the latter on the working condition 2, and 3 (diversion ratio was 10.0% and 25.0%). At the inlet pressure was greater than 0.3 MPa, the simulated result was greater than the measured result on the three different working condition. On the basis of the experiment, this paper analyzed the speed distribution, turbulent kinetic energy distribution and static pressure distribution of the centrifugal separator by applying computational fluid dynamics (CFD) software with the high-silt content water as micro-irrigation water source in water shortage areas. The results showed that velocity in centrifugal separator was distributed along the tangential, axial and radial directions, and the velocity distribution had symmetry along the radial direction. The turbulent kinetic energy of the centrifugal separator had symmetry, and the distribution from the middle to the wall on both sides became gradually smaller. The static pressure distribution of the centrifugal separator had symmetry, and the distribution from the wall on both sides to the middle became gradually smaller. The results provide data support for optimization of parameters for centrifugal separator in microirrigation.