Abstract: Dendritic silicon-based nanoparticles (DSNs) have center-radial pore channels different from the conventional mesoporous silica. A hierarchical pore structure of DSNs can typically comprise the micropores (< 2 nm), mesopores (2~50 nm), and macropores (> 50 nm). Specifically, the silica fibers or wrinkles are aligned in a center-radial orientation, and then DSNs can form the central-radial pore channels among these structures. The pore sizes are progressively enlarged from the core of the particle to its surface. There are some advantages of the DSNs' properties, such as the high drug-loading capacity, strong adhesion, excellent stability, excellent biocompatibility, adjustable pore size, and easily modifiable surfaces. The promising prospects can be applied to fields such as drug delivery, adsorption, catalytic conversion, and bioimaging. This article aims to introduce three synthesis approaches for the DSNs: the microemulsion, biphasic interface method, and aqueous-phase synthesis. Firstly, the systematic review was proposed to explore their formation mechanisms. In the microemulsion, the water, oil, and surfactants were formed into a thermodynamically stable system. Surfactant molecules with the hydrophilic or hydrophobic groups were aligned directionally at the water-oil interface to form the spherical aggregates, thereby reducing the interfacial tension. The biphasic interface method was used to offer a relatively simpler operation. However, a large amount of the organic solvents was required in the reaction for the scalable production. The immiscible oil and water phases were formed on the upper and lower reaction layers. The particle morphology was dominated by interfacial tension and reaction rates at the interface, leading to challenges in the precise control. The aqueous-phase synthesis** occurred entirely in water without any organic solvents, under mild reaction conditions. Secondly, current research highlighted the key influencing factors of the DSN formation. Moreover, the DSN pore structures were regulated for the precise control over morphology and structure, including the silicon source dosage, surfactant types, solvent composition, catalysts, and reaction temperature. The applications of the DSNs in agriculture were also reviewed, thus covering plant protection, pesticide residue detection, adsorption, and food quality monitoring, fruit and vegetable preservation. In plant protection, the DSNs were primarily used to load the enzymes and pesticides. The controlled-release nanopesticide was constructed for effective pest eradication. The DSNs were functionalized with the aptamer complementary chains or antibodies. The nanobiosensors were developed to detect pesticide residues, bacteria, and fungi in food, indicating the remarkable sensitivity. Additionally, the DSNs-based nanocatalysts were used to effectively scavenge ethylene during fruit/vegetable storage, delaying quality loss, decay, and spoilage. Finally, the prospects of DSNs were outlined in the agricultural applications. While the DSNs synthesis was selected to regulate their morphological structures. But it is still lacking in the precise strategies to control and prepare the nanoparticles with the center-radial pore channels and small-mesoporous composite structures. The hollow-cavity DSNs were also modulated after formation. The promising directions were also proposed to fill these gaps represented in the future. Additionally, the more straightforward and efficient synthesis can be essential to the large-scale, high-quality production of the DSNs. Furthermore, the DSNs remain relatively underexploited to combat the plant pathogen-induced diseases and weed control in agriculture. Much effort should be prioritized to tailor and evaluate the agricultural nanotechnologies, such as the nanoantibacterial agents, nanopesticides, nanoherbicides, biosensors, and adsorbents. This review can also provide valuable insights to construct promising nanopesticide systems.