Abstract: In order to explore the artificial reproduction of Gymnocypris potanini firmispinatus, on January 10, 2017, the wild population of Gymnocypris potanini firmispinatus was collected in Shigu Town. On February 20, 2017, the artificial reproduction study of the fish was carried out, and 18 groups were artificially induced to spawn. The induced birth rate was 66.67%, the fertilization rate was 61.32%, and 9200 artificially fertilized eggs were obtained for the first time. Gymnocypris potanini firmispinatus fertilized eggs were hatched at（14.02±025）℃ for 204 hours, and a total of 6 thousand newly hatched larvae were obtained, with a hatching rate of65.2%.