Abstract: This paper took the core course of machinery specialty of Xinjiang Agricultural University Principles Machinery as an example, and in view of the problems existing in the traditional teaching process of this course, put forward four aspects of teaching reform measures, namely, the construction of teaching resource database, the reform of teaching mode, the design of teaching scheme,and the reform of assessment and evaluation system, and summarizes the results of hybrid teaching reform. The results show that this teaching mode is conducive to improving students’ enthusiasm for learning, enhancing students’ systematic design with basic theoretical knowledge, improving students’ practical and innovative ability, providing ideas for the teaching reform of relevant professional courses.