Abstract: In order to investigate the yield potential and resistance of new colored rice varieties, Hongliangyou 8012 and Shennongyou Hongsimiao, and provide data support for their approval and popularization, a randomized block test was conducted in Menghai County, in 2020, with the local red rice variety Hongdao No.8 as the control. The results showed that:（1）the yields of Hongliangyou 8012 and Shennongyou Hongsimiao were 653.40 kg/0.067 hm~2 and 664.80 kg/0.067 hm~2, respectively, which were 31.19% and 32.37% higher than that of Hongdao 8（P＜ 0.01）; The reason is that the number of grains per panicle of Shennongyou Hongsimiao and Hongliangyou 8012 was significantly higher than that of Hongdao No.8, increased by 45.93% and 49.33% respectively.（2）Shennongyou Hongsimiao and Hongliangyou 8012 had strong disease resistance, showing that they were not susceptible to leaf blast, panicle neck blast and sheath blight. Shennongyou Hongsimiao was lightly susceptible to white leaf blight（10.00%）, while Hongliangyou 8012 was not susceptible to white leaf blight. Hongdao No. 8 was highly susceptible to leaf blast and panicle neck blast, while white leaf blight was moderately susceptible（43.33%, 50.00% and 6.67%）. The results showed that Hongliangyou 8012 and Shennongyou Hongsimiao seedlings had high yield potential and disease resistance.