Abstract: In order to explore the application effect of different organic fertilizers on rice production, field experiments on rice fertilizer efficiency were carried out. The results showed that increased application of organic and organic inorganic replacement BB fertilizer could effectively improve effective ear, seed setting rate and yield of rice. Under the same nitrogen level, compared with conventional fertilization, the yield of commercial organic fertilizer increased by 5.1% and decreased by 7.5%, that of bio-organic fertilizer increased by 10.9% and increased by 0.14%, and that of organic and inorganic compound fertilizer increased by 4.0% and decreased by 0.03%. The effects of bio-organic fertilizer on rice yield, economic benefit, nitrogen partial productivity and nitrogen agronomic efficiency were better than those of commercial organic fertilizer and organic and inorganic compound fertilizer.