Abstract: The climatic factors in Zaozhuang City in recent 30 years were analyzed by the method of literature and field investigation, and the effects of climate factors such as temperature, precipitation and sunshine on the growth of Dioscorea esculenta were clarified. According to the common meteorological disasters in Zaozhuang City, the corresponding industrial development strategies should be formulated from the aspects of strengthening meteorological monitoring and early warning, optimizing Dioscorea esculenta planting area and adjusting the structure of advantageous producing areas.