Abstract: This paper makes statistics and regression analysis on the yield changes of 125 soybean varieties approved in Henan Province from 1985 to 2020. The results showed that there was a significant linear regression relationship between the yield of approved soybean varieties in regional test and production test and the approved year, and the yield showed an upward trend as a whole. From1985 to 2015, the maximum output of regional test increased gradually, and from 2016 to 2020, the maximum output of regional test decreased slightly compared with that from 2010 to 2015. Compared with the lowest value, the highest value of average yield in regional test and production test of approved varieties increased by 39.19% and 58.51% respectively.