Abstract: The effects of nicosulfuron and 2,4-D butyl ester on leaf area, plant height, root traits, yield, plant control efficiency and safety of three maize varieties Zhengdan 958, Xianyu 335 and Jingke 968 were studied by split plot design. The results showed that nicosulfuron herbicide had better effect, higher safety and better resistance to Jingke 968.