Abstract: In view of the problems arising in the course practice of Numerical Control Technology in College of Mechanical and Electrical Engineering, such as students’ low learning initiative, teaching effect improvement is not obvious, and the combination of theory and practice is not sufficient, this paper proposed to carry out blended teaching practice reform for this course. Combine with reform measures such as flipped classroom, online and offline teaching mode, curriculum ideology and politics, and make full use of modern teaching means such as "nong da yun shang" network teaching platform to make the right to decide on learning to students,so as to tap students’ learning potential and improve curriculum quality. Through the blended teaching practice of this course, good teaching effect is obtained, and the teaching reform measures are put forward, which provides certain reference value for improving the teaching effect and promoting the realization of the goal of talent training.