Abstract: Red pomelo has high nutritional value and edible value, and the market demand is large, which promotes the development of the red pomelo industry. During the cultivation of red pomelo, whether the cultivation technology is standardized and whether the pest control is scientific is an important factor affecting the yield and quality of red pomelo. In order to meet the market demand for high yield and high quality, it is of great significance to do a good job in cultivation management and pest control of red grapefruit.Taking Sinan County as an example, this paper analyzed the key points of high yield cultivation technology of red pomelo, and discussed the main pest control measures of red pomelo.