Abstract: This paper took the Picea asperata Mast. in Dibu County as the research object, investigated the effect of needle spraying and crown spraying on the control of Picea asperata Mast.leaf rust, and analyzed and compared the decline rate of the disease plant after the application of different insecticides. The results showed that the decline rate of infected plants was 80.36%. At the end of May, spraying the crown with 500 times solution of dirustum sodium had a good effect on the control of leaf rust, and the reduction rate of diseased plants reached 86.61%.