Abstract: Under the zonal composite planting mode of soybean and maize, should attach great importance to the prevention and control of diseases and pests, combine the occurrence trend of diseases and pests, formulate scientific prevention and control technical measures, ensure the compatible and coordinated development of soybean and maize, and thus achieving increased production and income. Taking Fengshan County as an example, this paper made an in-depth analysis on the key points of soybean and maize strip composite planting technology and the measures of disease and pest control.