Abstract: Taking the superior Capsicum annuum Mintianhong from Longdong area as the research object, this paper explored the effects of different fertilizers on the growth, yield and quality of Capsicum annuum cultivated in steel frame greenhouses. The results showed that compared with no fertilizer application, applying organic fertilizer and microbial fertilizer can promote the growth of Capsicum annuum plants, increase fruit yield, and improve fruit quality. Among them, the effect of microbial fertilizer is the best.