Abstract: The field experiment of 7 fungicides control of fruit blotch disease showed that the control efficacy of thiamethoxam 1 000 times liquid stem and leaf spray and Pseudomonas Fluorescence 750 times liquid stem and leaf spray for three times were significantly higher than that of other treatments, ranging from 71.09%～81.04% and 65.80%～73.49%, and the yield was recovered 46.34% and 43.67%. At the same time, compared with the traditional control method using copper hydroxide, thiamethoxam could reduce the pesticide usage by 60.0%, and Pseudomonas fluoresceae could reduce the pesticide usage by 46.7%. Therefore, it is suggested to use Pseudomonas fluoresces in the production practice to control fruit blotch disease.