Abstract: Taking excellent maize variety Heyu 19 of Heze City as the research object. The effects of different fertilization methods on the number of grains per ear, ear size, grain quality, hundred grain quality and yield were evaluated. The results showed that the growth, development and yield of fertilized plants were significantly better than those of unfertilized plants, and the growth, development and yield of plants with phased topdressing were significantly better than those of maize plants with one-time fertilization. The growth, development and yield of maize plants with different fertilizer amounts under the same fertilization method were not significantly different. It can increase the green leaf area in the later growing period of maize, prolong the functional period of leaves and slow down the process of crop aging.