Abstract: Yiwu Yangping Fruit and Vegetable Professional Cooperative launched an experiment on the anti premature aging and quality improvement of Jinxiangyu melon.From the growth process, after the use of shitebao EM probiotics and supporting technologies in the experimental area, the resistance to powdery mildew and downy mildew in the experimental area is better than that in the control group. The expansion speed of melon young fruit in the expansion stage is much faster than that in the control group, the weight of a single individual exceeds more than 1/3 of that in the control area, the single yield increases by 400 kg/0.067 hm~2, and the sugar content and flavor are significantly better than those in the control group. The incidence rate of premature senescence in melon at maturity is below 1%.