Abstract: Liangzhou District is a large agricultural area, maize is the local advantage, leading food crop and cash crop, to ensure the safe and stable growth of maize is of great significance. When maize is growing, the seed quality is an important factor affecting the yield and quality of maize. If the seed quality is poor, the yield and quality of maize can not be effectively guaranteed. Compared with ordinary maize, seed maize has the advantages of high scientific and technological content, high yield and high benefit, and also has higher requirements for cultivation technology. In order to ensure the yield of seed maize, it is of great significance to do a good job in cultivation and management. Based on this, taking Liangzhou District as an example, the technical measures for high yield cultivation of seed maize were studied deeply.