Abstract: In order to explore the suitable fertilizer amount for Juglans regia planting in Zezhou District, 6 treatments were set up to explore the effects of different fertilizer amount on Juglans regia yield and quality. The results showed that the application amount of fertilizer had significant effects on the appearance index, yield and nutrient content of Juglans regia, and the yield and quality of Juglans regia were the best when the annual application amount of special Juglans regia fertilizer was 3～3.5 kg/plant. The fertilization amount can be widely promoted and applied in Juglans regia production in Zezhou County.