Abstract: The high-yield and disease-resistant variety of potato named Jinshu NO.16 is mainly popularized in Shanxi, Inner Mongolia, Shaanxi and Gansu, etc. Especially in main potato production areas in Shanxi Province, the promotion area of Jinshu NO. 16 could take 60% of all promotion areas of all the varieties of potatoes in Shanxi. Potato degeneration is always one of the biggest problems that happens during the promotion processes of all varieties of potatoes. The degeneration of potatoes could reduce the production of potatoes, decline the quality of potatoes, and even severely disrupt the economic benefits of potatoes. Producing high-quality and qualified virus-free seed potato minitubers by using the technologies of meristem tip culture, and standardized virus-free seed potato minitubers is the way to improve the output and quality of potatoes. High-standard virus-free seed potato is the most effective way to improve the economic benefits of Jinshu NO.16.