Abstract: Goat gastrointestinal nematode disease is a parasitic disease caused by a variety of nematodes. The insects are diverse and can be seen everywhere. Therefore, the probability of mixed infection is high. The disorder of intestinal digestion and absorption function of sick sheep is also very common, resulting in the normal growth of goats and even the death of sick sheep. In order to avoid or reduce the occurrence of the above events, this paper analyzes and studies the disease, and expounds the corresponding prevention and control measures.