Abstract: To find out the optimized water and fertilizer management,field experiments were conducted to investigate the coupling effects of different amounts of water and fertilizers on water consumption,dry matter accumulation on the ground,wheat yield,water use efficiency,nitrogen partial fertilizer productivity as well as economic benefits.Experiments included three levels of irrigation,i.e.60%ET_c（I1,300.0 mm）,75%ET_c（I2,370.0 mm） and ET_c（I3,495.0 mm）,and three levels of nitrogen,i.e.180.0 kg/hm~2（N1）,255.0 kg/hm~2（N2） and 330.0 kg/hm~2（N3）.The irrigation had a significant effect on the water consumption,and water consumption was increased with the increase of irrigation quota.Only appropriate water and fertilizer ratio can obtain higher dry matter accumulation on the ground,yield and economic benefits,and excessive water and fertilizer input would not increase sustainable output and income.Yield,water use efficiency,nitrogen partial fertilizer productivity and economic benefits had significant correlation with water and fertilizer.The quadratic regression equations of each index and water and fertilizer were established and the corresponding water and fertilizer amount of the maximum value of each index was 410.0 mm,260.0 kg/hm~2,370.0 mm,260.0 kg/hm~2,410.0 mm,180.0 kg/hm~2,400.0 mm,250.0 kg/hm~2,respectively.By regression and spatial analysis,it was concluded that the yield,water use efficiency and economic benefits reached no less than 95%of their maximum values simultaneously when the irrigation quantity was 359.8～428.9 mm （72.6%ET_c～87.5%ET_c） and the nitrogen application was 225.4～280.9 kg/hm~2,which can provide a scientific basis for irrigation and fertilization optimization in study area and other regions with similar environments.