Abstract: To explore the applicability of the DNDC model in simulating N₂O emission from red soil slope farmland, two tillage treatments（conventional tillage and no-tillage） were set up for peanut field in northern Jiangxi Province. Field in-situ observation experiments of N₂O emission were carried out for three consecutive years（2019—2021） by static box-gas chromatography to study the characteristics of N₂O emission and the simulation effect of DNDC model under different tillage treatments. The results showed that the DNDC model had a good simulation effect on soil temperature in 0～10 cm（the correlation coefficient r was 0.86～0.87） and crop yield（r was 0.90） under different tillage treatments. The model could effectively simulate the fluctuation of N₂O emission which caused by fertilization and rainfall during peanut season, as well as the peak of N₂O emission under conventional tillage. However, this model would underestimate the N₂O emission peak and its total amount to some extent under no-tillage, and had a smaller response to rainfall which was below 16 mm. Soil pH value and fertilization amount had the greatest impact on N₂O emissions from sloped peanut field on red soil. Rainfall, soil organic carbon and clay content were also important factors affecting N₂O emissions. According to simulate N₂O emission and peanut yield under different amount of fertilizer application in 2019, it was found that the application amount of nitrogen fertilizer should not be less than 76.54 kg/hm~2, and should not exceed 106.78 kg/hm~2. The research results can provide theoretical basis for optimizing crop planting and reducing agricultural greenhouse gas emission in red soil slope farmland.