Abstract: In order to study the influence of different guide vane parameters on the hydraulic perfor-mance of box culvert axial-flow pumps, the orthogonal design method was adopted, and the number, relative positions and sweep angles of guide vanes were selected as design factors. Three levels of factors were selected for combination, and numerical simulation was used to study the influence of the above factors on the pump device efficiency, the axial uniformity of the outlet flow channel, the hydraulic loss of the guide vane body and the average vortex angle at the outlet, and finally the optimal design scheme was determined comprehensively. The results show that when only the parameters of the guide vane are changed, the number of guide vanes has a greater influence on the average vortex angle at the outlet of the guide vane and the axial uniformity of the outlet flow channel. The relative position of the guide vane plays a dominant role in the influence of the efficiency of the pump device and the hydraulic loss of the guide vane body. With the increase of the sweep angle of the guide vane, the pump device efficiency, the axial uniformity of the outlet flow channel, and the hydraulic loss of the guide vane first increase and then decrease, but the average vortex angle is less affected. Comparing the results of numerical analysis and model test, the efficiency is basically consistent with the design conditions, and the head is within the allowable range of error range. The research results provide a theoretical basis for the optimal design of box culvert axial-pump.