Abstract: The long-distance water transmission system after the pump is prone to negative pressure when the pump is deenergized. A pump-stop water hammer protection scheme of pressure regulating tower combined with end regulator valve was proposed, and a mathematical model of the hydraulic transition process was established based on the characteristic line method of transient flow calculation to simulate the whole process of pump-stopping water hammer. Combined with the actual project, the minimum area of the pressure regulating tower of the conventional pressure regulating tower protection scheme was explored, and the parameter selection principle of the water hammer protection scheme of the pressure regulating tower set after the pump combined with the end regulator valve linkage was gi-ven, and the influence of the water hammer protection scheme of the conventional scheme and the water hammer protection scheme of the pressure regulating tower set behind the pump combined with the end regulator valve linkage closure on the water hammer of the pump was stopped. The results show that the area of the conventional scheme voltage regulating tower is 1 100 m~2. The protection scheme of the pressure regulating tower combined with the linkage closing of the end regulator valve will cause the pipeline positive pressure to be too large, while it closes slowly to lead to insufficient water flow return capacity of the pipeline. By selecting the appropriate end regulator closing time, under the premise of meeting the system water hammer protection standards, the area of the pressure regulating tower can be effectively reduced.