Abstract: In order to establish a set of salt tolerence material evaluation system for grain sorghum, this study used a combination of indoor simulation and field identification to study the response of different sorghum materials to salt stress. The simulation experiment at the seedling stage showed that the materials 09305 R, 67 B and 363 C had good growth, fast growth rate, and strong salt tolerance; materials 10337 B, and Ji 16 had low relative growth indicators, slow growth, and weak salt tolerance. The characteristics of other materials were between the first two; Correclation enzyme activity, dry matter accumulation content in leaves at seedling stage, joint stage, heading stage, maturity stage and Na⁺ content and K⁺ content in leaves at seedling stage were determined in field experiment. Results showed that the content of SOD and CAT was positively correlated with the salt tolerance of the material under salt stress. The dry matter accumulation was in the order of maturity stage＞filling stage＞joint stage; among them, the sorghum seedling stage was the salt-sensitive stage, and there were significant differences between treatments, and salt-tolerant materials showed higher growth ability to increase the content of dry matter; Na⁺ of sorghum seedlings showed an overall upward trend. Under salt stress conditions, the increase of the salt-tolerant materials was significantly smaller than that of the salt-sensitive materials; The difference K⁺ content of sorghum leaves was not significant; The leaf enzyme activity showed a extremely significant positive correlation with germination rate, germination potential., and the correlation coefficients were 0.92 and 0.97, respectively. The correlation between root length and germination potential was also high, and the correlation coefficient was 0.87. From the 10 characteristic roots, the contribution rate of the first principal component was 71.38%, of which the germination rate, germination potential and leaf enzyme activity the first main component values were relatively high, which mainly reflected the seed germination and growth status and resistance indicators, which could be called growth factors; The contribution rate of the second main component was 11.25%, and among the second main components, of which the seedling length and growth rate were relatively high, which mainly reflected the growth status of sorghum; The cumulative contribution rate of the first two principal components reached 92.49%; Using cluster analysis, the 15 sorghum parent materials were divided into three categories: salt-tolerant, medium-salttolerant, and salt-sensitive materials.