Abstract: In order to study the parents utilization and kinship of white varieties approved by He’nan Province, 419 wheat varieties registered by He’nan Province and their parents combinations were analyzed from 2000 to 2020. The results showed that according to the utilization frequency, a total of 32 core parents were identified for breeding and utilization since 2000, among which Zhoumai 16, AK 58 and Zhoumai 22 were highly used, and the frequence were 65 times, 57 times and 36 times, respectively. Cluster analysis of the 32 core parents was conducted by pedigree method, and they were divided into six groups according to the genetic relationship. Study showed that group Ⅵ was most frequently used in breeding since 2000, including 19 core parents such as AK 58, Zhoumai 22, Zhoumai 18, Xinmai 18 and Zhengmai 366.They were mainly derived from Baofeng 7228, Wen 2540, Zhoumai 9, Xinmai 9, Zhoumai 13/Zhoumai 16 directly or combinations of each other. At the same time, clustering analysis of 419 cultivars was carried out, and the results were basically consistent with those of core parents. This research defined the genetic relationships among core parents, breeding varieties, breeding varieties and core parents, which laid a good foundation for reasonable utilization and further genetic improvement of wheat germplasms.