Abstract: To explore the slow release effect of agricultural plant Jiaosu on sorghum seeds under drought stress, using Hongyingzi and Hongzhenzhu seeds as experimental materials, the germination rate, germination potential, germination index, and other indicators of two sorghum seeds under different conditions were measured, and the effects of agricultural plant Jiaosu on the germination and growth of sorghum seeds under drought stress were studied. The results showed that with the increase of PEG-6000 solution concentration, the germination rate, germination potential, and germination index of the two sorghum seeds showed a downward trend. When the PEG-6000 solution concentration was 20%, the germination rate, germination potential, and germination index of Hongyingzi and Hongzhenzhu decreased by 52.52%, 14.44%, 6.32, and 52.22%, 15.55%, 4.22, respectively, compared to ck, with significant differences. Different concentrations of agricultural plant Jiaosu had different effects on seed germination. When the concentration was diluted to 1200 times, the germination effect of the two sorghum varieties performed best. The germination rates of Hongyingzi and Hongzhenzhu increased by 0.92% and 5.56% compared to ck, respectively, and the seed mold rate decreased by 8.89% and 7.63% compared to ck, respectively. When sorghum seeds under drought stress were treated with agricultural plant Jiaosu diluted by 1 200 times, the inhibition of seed germination was relieved, and the most significant effect was achieved when the concentration of PEG-6000 solution was 20%. The germination rates of Hongyingzi and Hongzhenzhu increased by 16.67% and 37.78%, respectively, and the mildew rates decreased by 9.03% and 10.78%, respectively. This indicated that the concentration of agricultural plant enzymes diluted by 1 200 times was the most suitable germination concentration for Hongyingzi and Hongzhenzhu, and this concentration of agricultural plant Jiaosu could relieve the effects of drought stress on sorghum seeds.