Abstract: In order to prevent the rise of groundwater level becoming a disaster and provide guidance for the rational allocation and utilization of water resources in Bayin River Basin of Qinghai Province,the zoning map of groundwater level rise,the dynamic curve map of river runoff and groundwater,and the annual average runoff curve for many years were plotted. The response characteristics of groundwater to flood infiltration were systematically analyzed by using the point-surface combination method in Bayin River Basin. The results obtained were listed as follows. During the flood season,the groundwater level of Gobi Beach increased significantly,and the closer the region was to Bayin River,the faster the groundwater response was and the greater the water level rose,which could be up to more than 10 m. On the contrary,the farther the region was from Bayin River,the more the groundwater response lagged,the more slowly the water level rose. Besides,the critical flow rate of flood disaster in Bayin River was determined to be 4. 07 × 108 m3.Finally,the prevention and control measures are proposed to reduce the infiltration of floods by the reduction in the infiltration of river water,the increasing discharge of groundwater and the implementation of the prevention and control of source-saving discharge in Bayin River Basin.