Abstract: Biobased epoxy resin(DGEBDB) was created using 6-(bis(4-hydroxy-3-methoxyphenyl) methyl) dibenzo c, e oxyphosphate 6-oxide(BDB) and epichlorohydrin(ECH) as raw materials and tetrabutylammonium bromide(TBAB) as catalyst. Then, it was solidified with bisphenol A(DHABA), a curing agent containing β-amino alcohol structure, to obtain a bio-based flame retardant and antibacterial epoxy resin(EB/DHABA) with both intrinsic antibacterial and intrinsic flame retardant properties. The relationship between structure and performance was investigated by varying the ratio of DGEBDB to commercial epoxy resin E51. The structure of DGEBDB was characterized by nuclear magnetic resonance spectroscopy(¹H NMR). The curing behavior, thermal, mechanical, antibacterial and flame retardant properties of epoxy resin were tested and analyzed by FT-IR, TG, paint film impactor, colony counter and vertical combustion tester. The results showed that EB/DHABA had been successfully prepared, the resin had excellent comprehensive properties, and the glass transition temperature could reach 130.62℃. When the content of DGEBDB in the system was 10%, the crosslinking density of the system was highest, which was 3 519 mol/m³. T_10% was about 350℃, and it decreased with the increase of DGEBDB addition. The pencil hardness of the paint film could reach up to 5H and it had good impact strength and solvent resistance. It also had good killing effect on E. coli and S. aureus, with a sterilization rate of 99.4%. The results of vertical combustion test revealed that when the content of DGEBDB in the system reached 30%, the flame retardant effect was the best, and UL-94 grade could reach V-0 grade.