Abstract: In this paper, the recent research progresses in polyhydroxybenzophenones were reviewed. The different synthesis methods of polyhydroxybenzophenones, mainly the synthesis of 2,4-dihydroxybenzophenone by condensation reaction of benzoyl chloride, benzoic acid and trichlorotoluene with resorcinol, as well as other related synthesis methods of polyhydroxybenzophenones were introduced and compared in detail.It was suggested that exploitation of synthesis method with high efficiency, energy conservation, low-cost and environmental protection is the development trend at home and abroad in the future.