Abstract: Bamboo residues were used as raw materials to prepare bamboo liquefied resin by liquefying, and then the bamboo liquefied resin was modified by adding polyether polyol, and the preparation process parameters were optimized by orthogonal method.The results showed that the optimal preparation process parameters were the total weight of foaming system 200 g, resin addition amount 30%, curing agent addition amount 7.5%, PM-200 addition amount 20%, polyether polyol addition amount 1%, addition of foaming agent 10%, and surfactant addition amount 8%. Under this process, the apparent density of the foaming cultivation substrate material was 0.041 9 g/cm³, the leaching pH was 2.61, the water absorption rate was 85.93%, and the water retention rate was 97.68%.Through FT-IR, TG, SEM and other characterization, it was found that after adding polyether polyol, the pulverization of bamboo powder liquefied resin foaming cultivation matrix material was much reduced, and the material had good cell structure and good thermal stability. And the weather resistance test found that the main functional groups of cultivation matrix material didn't change in indoor and outdoor applications and it had good weather resistance.