Abstract: In order to comprehensively evaluate the level of high-quality development in the Beijing-Tianjin-Hebei（BTH） region, a high-quality development evaluation index system is constructed from five dimensions: innovation, coordination, greenness, openness and sharing. This system employs entropy-coefficient-of-variation comprehensive weighting method to assign weights to the indices. Then, a comprehensive evaluation index model is constructed by means of the linear weighting method, so as to quantitatively measure the level of high-quality development of the water-energy-food（WEF） system in the BTH region. In addition, the key factors and dimensions affecting the WEF system are analyzed by the gray relational model. The results show that the comprehensive evaluation index of the BTH WEF system showed an upward trend from 2011 to 2021, and the mean values of the three provinces and municipalities on the spatial scale were in the order of Beijing＞Hebei＞Tianjin; the indices of the BTH WEF system in each dimension showed different spatial and temporal characteristics, among which the sharing dimension showed a downward trend, and the spatial difference in the innovation dimension was the most significant; the food production, percentage of domestic energy consumption, energy consumption per 10 000 yuan GDP, percentage of domestic water consumption, percentage of energy consumption in the tertiary sector etc. are the key factors affecting the high-quality development of WEF system, and the coordination and sharing are the key dimensions. The results of the study can provide a theoretical basis for the high-level management of regional resources.