Abstract: In order to solve the problem that the control signal sent by the upper computer of the unmanned driving system does not match with the receiving signal of each ECU,a vehicle controller is designed.It includes hardware circuit design and software program development.The hardware circuit includes high and low variable drive circuit, can communication circuit and SPI communication circuit, etc.The software program includes the application layer code automatically generated based on Matlab-Simulink model and the bottom driver written by hand.The test shows that the vehicle controller can successfully convert the horizontal and vertical control signals sent by the upper computer of the unmanned driving system into signals that can be received by each ECU,and realize safe and real-time control.