Abstract: Taking the centrifugal air compressor fuel cell system as the research object, a simulation model of the air subsystem of the fuel cell system was established, and an anti-surge control strategy based on the fuzzy control theory was designed, and the effectiveness of the designed anti-surge control strategy was simulated and analyzed, based on Matlab/Simulink software.The simulation results show that the strategy can change the bypass flow rate, by adjusting the opening of the bypass valve, at the right time to avoid effectively the occurrence of the surge condition, and ensure the stability of the system, while achieving good control quality.