Abstract: In order to overcome the disadvantages of UV-curable acrylate pressure-sensitive adhesives with high odor and oxygen inhibition polymerization, the monomers butyl acrylate（n-BA）, 2-ethylhexyl acrylate（2-EHA）, glycidyl methacrylate（GMA） and functional monomers acrylic acid（AA） and hydroxyethyl methacrylate（HEMA） were used as raw materials. Dodecyl mercaptan（DDM） was used as the chain transfer agent and dibenzoyl peroxide（BPO） was used as the initiator for free radical polymerization to synthesize acrylate prepolymers containing epoxy groups. Then the cationic UV initiator 6976 was added to obtain self-crosslinked epoxy acrylate pressure-sensitive adhesive by coating and UV light initiation. The effects of DDM, GMA and photoinitiator dosage on the performance of pressure-sensitive adhesives were investigated during the experiments. The results showed that the pressure sensitive adhesive with the dosage of 12.5% of GMA, 0.26% of DDM and 2% of photoinitiator 6976 had the best performance. The initial adhesion of pressure-sensitive adhesive reached 11.1 N/25 mm, peeling force reached 14.6 N/25 mm, shear strength reached 9.2 N/12×12 mm~2, good heat resistance at 80 ℃ for 4 h, and no adhesive loss after peeling. The prepared pressure-sensitive adhesive is easy to be coated at 50 ℃, without active diluent, no irritating odor, no oxygen barrier, and so on, which has great application prospects in industry.