Abstract: In order to study the dynamic shock wave characteristics of detonation grenade near the ground, the attenuation law and non-lethal characteristics of shock wave of a 64 mm detonation grenade at different motion speeds and different heights from the ground were simulated and analyzed by AUTODYN software. The results show that the gain effect of dynamic explosion condition on shock wave decreases with the increase of distance. With the increase of motion speed, the overall gain effect of overpressure value increases, and the injury effect on personnel can reach serious damage. As the detonation height increases, the intensity of the incident wave when the shock wave itself reaches the ground gradually decreases, and the corresponding ground reflection intensity of the shock wave decreases. Under the condition of 100 m/s dynamic explosion, when the detonation height is 4 m, the detonation grenade will cause moderate damage to some people, and the people outside the horizontal distance of 2.5 m are safe and harmless. When the detonation height is 5 m, the detonation grenade overpressure will not cause damage to the people below.