Abstract: In order to investigate the influence of living sand barriers on soil moisture and nutrients in sandy soil, this study selects wheat living sand barriers, alkali grass and oats living sand barriers, and nylon bag mechanical sand barriers in the Qinghai Province’s Gonghe Basin as research objects. Field surveys and indoor measurements are used to compare and analyze the effects of living sand barriers on soil moisture, organic matter content, total nitrogen, total phosphorus, and total potassium in sandy soil. Results show that:（1） the soil quality moisture content in the wheat living sand barrier and the alkali grass and oats living sand barrier areas has reached 3.48% and 4.26%, respectively, which are significantly higher than that of the sand drift area（P＜0.05）, and are 2.13 times and 2.47 times that of sand drift, respectively.（2） Although the organic matter, total phosphorus, and total potassium contents in the soil of the wheat living sand barrier and the alkali grass and oats living sand barrier areas are higher than those of the nylon bag mechanical sand barrier and the sand drift area, they does not reach a significant level（P＞0.05）, and only the total nitrogen content in the living sand barrier areas is significantly higher than that of the mechanical sand barrier and the sand drift area.（3） The setting of living sand barriers has a significant improvement effect on soil moisture and total nitrogen content in sandy soil（P＜0.05）, which is conducive to the formation of sandy soil and the reversal of desertification.