Abstract: Aeration is one of the ecological restoration techniques to solve the water bodies affected by hypoxia. However,dissolved oxygen variations in water will change energy flow and mass balance of solid-liquid interfaces,which lead to resuspension release of heavy metals adsorbed bottom sediments. Taking an organic polluted water body in Zhenzhou District of Yangzhou City as research topic,the aeration depth as the control variable,this paper studies the release law of heavy metals from bottom sediments under different aeration modes. The results of field experiments show that different heavy metals in the sediments have different responses to aeration. Cd increases with the co-precipitation of Fe and Mn. The release of Cu and Fe is sensitive to the change of pH,while the release of Zn and Pb is coordination effect of H⁺ and co-precipitation of Fe and Mn. From the sediment remediation effect,shallow aeration is conducive to the release of heavy metals of sediments,reduce the heavy metal pollution in sediments. The remediation effect of shallow aeration is better than that of deep aeration. During aeration,nitrogen-containing colloid in water flocculates and settles in sediments. However,the amount of phosphorus absorbed by the oxides in the sediment surface is far less than the amount of anaerobic phosphorus released.