Abstract: In order to achieve harmony between human and water and sustainable economic and social development,this paper designs a water resources carrying capacity evaluation model based on the system dynamics model（WRCC-SEM）,including economic and social modules,water resources pressure modules,water resources supporting capacity modules,water resources pressure analysis ＆ carrying capacity calculation module. Taking the main urban area of Zunyi City as the study area,the WRCC-SEM model of the main urban area of Zunyi City is constructed,and the authenticity of the model is verified with the statistical data of the study area,and then the future water resources carrying capacity of the main urban area of Zunyi City is evaluated and analyzed. The results show that the model simulation values are basically close to the corresponding statistical values in 2015 to 2019,the absolute relative errors are less than 15% in each year,which proves the rationality of the model structure and the effectiveness of the simulation. From the perspective of the potential carrying capacity of water resources,the amount of water resources in the main urban area of Zunyi City can support economic and social development. However,from the perspective of engineering water supply,from 2020 to 2035,due to engineering water shortages,the pressure relationship of water resources is overload in some years,including the year 2035,the main urban area of Zunyi City will be limited in economic and social development. In order to increase the carrying capacity of regional water resources and coordinate the relationship between water resources and economic and social development,the managers need rationally arrange the scale of water source projects and the timing of their commissioning.