Abstract: Parameter calibration is an important research content of hydrological model. The application of simple and efficient parameter calibration method can enhance the efficiency and promote the popularization of the model. In order to explore the application effects of the System Response Parameter Calibration Method in large-scale distributed hydrological models,SRPCM is applied to calibrate the parameters of VIC ideal model and actual model in Dapoling Catchment,based on the sensitivity analysis of parameters. The results in this study indicate that it is feasible and efficient to apply SRPCM to the VIC model;the VIC model is able to simulate the daily runoff in Dapoling Catchment effectively;the average Nash coefficients exceed 0.6 and the relative errors of runoff volume are below 8% during the calibration and validation periods. Therefore,SRPCM proves to be an effective and useful parameter calibration method.