Abstract: Based on the flood disaster mechanism and flood characteristics of the Minjiang Basin, the hydrological, topographic, hourly precipitation data, statistical yearbook, flood control projects and other data of the Minjiang Basin are collected and sorted out. Starting with the danger of flood risk, this paper selects vulnerability and disaster-bearing and defense ability, 17 evaluation indexes. The AHP analytic hierarchy process and the entropy weight method are used to obtain flood factor weight indicators of the Minjiang Basin, and the spatial differentiation characteristics of flood risk are analyzed in combination with the spatial analysis function of GIS, so as to quickly evaluate the flood risk zoning of the Minjiang Basin. It is conducive to the formulation of macro-flood control and disaster reduction policies and refined flood control response measures. The results show that the results of flood risk zoning in the Minjiang Basin are basically consistent with the flood disasters in recent decades. The distribution of the flood risk in the Minjiang Basin is closely related to its climate, topography, social economy, flood control projects and other factors. The difference of flood risk in the basin is high, and the high risk is concentrated on several counties and cities in Nanping, the upstream region.