Abstract: The hydraulic design of the impeller blade and guide vane was carried out for the super-large flow submersible tubular pump device with Q=100 m~3/s,and the optimization was carried out based on the orthogonal test method.The optimal pump device scheme was calculated by CFD to explore the external characteristics of the unit,and the hydraulic performance parameters of the two types of guide vane installation units with flush and uneven exit edges were compared and analyzed.The research results show that when the impeller hub ratio is0.4,the number of blades is 4 and the number of guide blades is 6,the efficiency of the pump unit is the highest,and the maximum efficiency of the pump unit is 80.52%.Under the working condition of 1.0Q_d,the pump head is 2.73 m and the efficiency is 74.68%.Under the working condition of 0.87Q_d,the pump head is 4.50 m,and the efficiency is 80.14%.Under the 1.12Q_d working condition,the pump head is 0.45m and the efficiency is 23.77%.From the parameters of head,efficiency and hydraulic loss of guide vane section,it is concluded that the hydraulic performance of the unit with uneven guide vanes placed at the water edge is better.The modeling method of impeller and guide vane and the optimization method combined with orthogonal test and CFD calculation have improved the hydraulic optimization efficiency and are suitable for popularization and application.Moreover,the research results of the calculation and analysis of the low head and super-large flow pump also provide a certain hydraulic performance reference for the large-scale development of submersible tubular pump.