Abstract: As the core equipment of hydroelectric power plants, hydroelectric generator units inevitably generate vibration and pressure pulsation problems during long-term operation. Long term vibration can accelerate the wear and fatigue of mechanical parts, reduce the lifespan and reliability of the unit, and may also lead to unstable operation of the unit, and even cause serious accidents, posing a threat to the safety of the power plant. These vibration and pulsation problems stem from multiple factors, including the dynamics of water flow, the design and manufacturing quality of impellers, and the complex interactions between the unit and the hydraulic system. These vibration and pressure pulsation issues have a negative impact on the performance, reliability, and safety of hydroelectric generators. Therefore, it is particularly important to conduct in-depth research on the vibration and pressure pulsation problems of hydroelectric generator units during operation and find effective solutions. This article analyzes the experimental data of Unit 3 of Ansha Hydropower Station and delves into the operational stability issues caused by pressure pulsation and vibration of hydroelectric generator units. By using the Wilcoxon rank-sum test and Pearson correlation coefficient to analyze the pressure pulsation, vibration, and swing signals during the operation of water turbine units, it was found that there is a strong correlation between the overall signals of hydraulic turbine units, especially in the swing signal. Finally, methods and strategies to reduce pressure pulsation and vibration issues generated during the operation of hydroelectric generator units were explored for the design, operation, and maintenance stages. By taking these measures, we can effectively reduce the negative impact of vibration and pressure pulsation, ensure the safe and stable operation of hydroelectric generator units, and contribute to the development of sustainable energy.