Abstract: In order to solve the problem of regional water shortage and water resource utilization, China has planned to build a complex water diversion system with multiple pumping stations in recent years to realize trans regional water transfer. This kind of project has the characteristics of long distance, multiple pumping stations, multiple water supply terminals, complex pipeline system, etc. It is difficult to achieve the goal of optimal dispatching and economic operation. Through a research on the key technologies of intelligent dispatching of the complex water diversion system in the Qingshui River basin of Ningxia, under the premise of ensuring the safety and quality of water supply, this paper adopts the method of combining mathematical simulation with on-site monitoring, through an intelligent analysis and optimal dispatching calculation, to quickly obtain an optimal operation plan, to achieve intelligent analysis, intelligent diagnosis, economic operation and dispatching decision-making of all stations along the line, and to improve the overall operation economy and operation efficiency of the system, effectively improve the assurance rate of water supply to achieve safe, efficient and economic operation.