Abstract: To solve the problems of complex and changeable material components and uneven flow in the drying process of sick and dead animals, a new type of double ribbon agitator was proposed.The fluid-solid coupling of the material in the chemical tank and the agitator was carried out using ANSYS Software. Modeling and simulation analysis was used to investigatethe material flow rate and distribution mechanism in the chemical vessel under different stirring speeds and combine the material flow line distribution in the drying vesselso as to optimize the structure of the agitator. Experimental and numerical optimization results showed that the maximum deformation of the double ribbon agitator was0.21 mm at a stirring speed of 10 r/min, and flow velocity of more than 80% of the materials in the chemical system reached 0.419 m/s. Compared with the single ribbon agitator, the material flow performance wasincreased by 20%, and the efficiency and quality of the drying process of sick and dead animals were improved.